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Lecturer(s)
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Vrzáková Radana, MUDr.
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Cibulka Roman, MUDr. Ph.D., MBA
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Večeřová Markéta, Mgr.
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Course content
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1.Basic chemical terminology. Elements and compounds, biogenic and toxic. 2.Essence and significance of metabolism. Basic substances in metabolism. The cells and the extracellular matrix. 3.Energy metabolism, its principles and main metabolic pathways. 4.The conversion of carbohydrates and lipids. 5.Metabolism of nitrogen compounds, conversion of amino acids and the formation of nitrogenous waste products. 6.Metabolism of proteins, porphyrins and nucleotides. The formation of bile pigments and urates. 7.Biological membranes, the nature of nerve impulses and nerve functions. 8.Specialities of muscle metabolism, muscle contraction. Creatinine and renal function. 9.Water, body fluids and their composition, acid-base balance and its disorders. 10.The biochemical nature of diabetes, behavior traits of diabetic tissues from the perspective of orthotist, signifikance of ischemia. 11.The biochemical nature of tumors and chemotherapy treatment, the impact of chemotherapy on the status of the tissues. 12.Basics of the biochemical diagnostics. 13.The materials used in orthotics and prosthetics, and their possible effect on the human body. 14.Basic Immunology, inflammatory allergic reactions to prosthetic materials, immunological reaction - fourth type. 15.Consultation, reserve, written credit test.
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Learning activities and teaching methods
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Multimedia supported teaching, Lecture with visual aids
- Preparation for comprehensive test (10-40)
- 25 hours per semester
- Contact hours
- 30 hours per semester
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Recommended literature
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JABOR, Antonín a kol. Vnitřní prostředí. 1. vyd.. Praha: Grada, 2008. ISBN 978-80-247-1221-5.
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Koolman, Jan; Röhm, Klaus-Heinrich. Barevný atlas biochemie. 1. české vyd. Praha : Grada, 2012. ISBN 978-80-247-2977-0.
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MASOPUST, J. Klinická biochemie. Praha:Karolinum, 1998. ISBN 80-7184-648-1.
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Matouš, Bohuslav. Základy lékařské chemie a biochemie. Praha : Galén, 2010. ISBN 978-80-7262-702-8.
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MURRAY, Robert K. et al. Harperova biochemie: a lange medical book.. 3. vyd., 4. české vyd., V H + H 3. Jinočany: H& H. ix, 872 s, 2002. ISBN 80-7319-013-3.
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Štern, Petr. Obecná a klinická biochemie : pro bakalářské obory studia. 2., upr. vyd. Praha : Karolinum, 2011. ISBN 978-80-246-1979-8.
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