Course: Molecular and Cell Biology

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Course title Molecular and Cell Biology
Course code CBG/MOBI
Organizational form of instruction Lecture
Level of course Bachelor
Year of study not specified
Semester Winter
Number of ECTS credits 3
Language of instruction Czech
Status of course Compulsory
Form of instruction Face-to-face
Work placements This is not an internship
Recommended optional programme components None
Lecturer(s)
  • Pavelka Jaroslav, Mgr. Ph.D.
Course content
1. Eukaryotic and prokaryotic cell - organelles, intercellular connections, chemical composition, cell vital functions 2. Cells - metabolism, movement, communication, transport, growth, reproduction - mitosis, meiosa, etc. 3. Structure of DNA, RNA, proteins, central dogma of molecular biology, genetic code 4. Structure of the prokaryotic and eukaryotic genome 5. Gene families, repetitive sequences, transposable element, organelle genomes 6. Replication, transcription and post-transcriptional modifications 7. Translations and post-translational modifications, regulation of gene expression, methylation and other DNA modifications 8. Cell cycle control, differentiation, apoptosis, mutation, repair, tumor diseases, operons, phage expression, controlled eukaryotic transcription, signal molecules 9. Methods of molecular biology - nucleic acid isolation, centrifugation, electrophoresis, restriction enzymes 10. PCR, cloning, NK labeling, hybridization 11. Sequencing, sequencing of the new generation 12. Chromatography, in vitro translation, FISH, DNA chips 13. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and Their Possibilities for the Future

Learning activities and teaching methods
Students' self-study, Self-study of literature, Textual studies, Lecture, Lecture with visual aids
  • Preparation for comprehensive test (10-40) - 26 hours per semester
  • Preparation for an examination (30-60) - 26 hours per semester
  • Contact hours - 26 hours per semester
prerequisite
Knowledge
know and control chemical nomenclature Know the biochemical nature of the events that take place in living organisms control biology and chemistry at the gymnasium level to know the cell construction at the gymnasium level to know the professional terms of general biology at the gymnasium level
Skills
use independent thinking and have the ability to study literature on the basis of the assigned task to specify the goals, results and conclusions of their own observation at the gymnasium level
Competences
N/A
learning outcomes
Knowledge
To know the structure and composition of viruses, eukaryotic and prokaryotic organisms.
Know the forms of genetic information, its transmission and adaptations.
Describe replication, transcription and translation.
To know and explain the dogma of molecular biology and describe all the processes that are related to it.
To know differentiation, apoptosis and other similar events taking place in the body.
Know PCR and other molecular biology methods.
Skills
Use basic terminology of molecular biology.
Suggests to use basic methods of molecular biology.
Competences
N/A
teaching methods
Knowledge
Lecture
Lecture with visual aids
Textual studies
Self-study of literature
Skills
Lecture
assessment methods
Knowledge
Combined exam
Test
Skills
Combined exam
Recommended literature
  • Alberts, B. a kol. Základy buněčné biologie : úvod do molekulární biologie buňky. Ústí nad Labem: Espero Publishing, 1998. ISBN 80-902906-2-0.
  • Alberts B. Molecular Biology of the Cell. New York: Garland Science, 2014.
  • Bresler, Semen Jefimovič. Molekulární biologie. Praha : Academia, 1979.
  • Kubišta, V. Buněčné základy životních dějů. Praha, 1998.
  • Kubišta, V. Obecná biologie. Fortuna Praha, 2000.
  • Romanovský, A. Obecná biologie : celost. vysokošk. učebnice pro stud. přírodověd. a pedagog. fakult. Praha : SPN, 1985.
  • Rosypal, S. a kol. Nový přehled biologie. Praha, 2003.
  • Rosypal, Stanislav. Přehled biologie. Praha : Scientia, 1994. ISBN 80-85827-32-8.
  • Rosypal, Stanislav. Úvod do molekulární biologie. 2.,rozš. vyd. Brno : Stanislav Rosypal, 1997.
  • Šmarda J. Metody molekulární biologie. Masarykova univerzita, 2010. ISBN 9788021038417.
  • Vodrážka, Zdeněk. Biochemie. Praha : Academia, 1996. ISBN 80-200-0600-1.
  • Vonka, Z. a kol. Kapitoly molekulové biologie. H&H Praha, 1992.
  • Žurovec, J. Molekulární biologie živočichů. Biologická fakulta JCU, 1999.


Study plans that include the course
Faculty Study plan (Version) Category of Branch/Specialization Recommended year of study Recommended semester
Faculty: Faculty of Education Study plan (Version): Studies in Mathematics (19) Category: Mathematics courses 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): Studies in Mathematics (18) Category: Mathematics courses 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): Information Technologies in Education (18) Category: Informatics courses 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): Technology and Design in Education (19) Category: Pedagogy, teacher training and social care 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): German Language in Education (18) Category: Pedagogy, teacher training and social care 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): Geography in Education (16) Category: Pedagogy, teacher training and social care 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): Biology in Education (15) Category: Biology courses 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): Physical Education in Education (13) Category: Physical education and sport 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): Geography in Education (19) Category: Pedagogy, teacher training and social care 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): Chemistry in Education (17) Category: Chemistry courses 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): Technology and Design in Education (17) Category: Pedagogy, teacher training and social care 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): Biology in Education (19) Category: Biology courses 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): Physics in Education (19) Category: Physics courses 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): Geography in Education (18) Category: Pedagogy, teacher training and social care 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): Chemistry in Education (14) Category: Chemistry courses 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): Chemistry in Education (19) Category: Chemistry courses 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): Information Technologies in Education (19) Category: Informatics courses 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): German Language in Education (17) Category: Pedagogy, teacher training and social care 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): Technology and Design in Education (16) Category: Pedagogy, teacher training and social care 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): Physical Education in Education (16) Category: Physical education and sport 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): Technology and Design in Education (18) Category: Pedagogy, teacher training and social care 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): Physical Education in Education (17) Category: Physical education and sport 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): Chemistry in Education (16) Category: Chemistry courses 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): Health Education (16) Category: Pedagogy, teacher training and social care 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): Biology in Education (18) Category: Biology courses 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): Biology in Education (16) Category: Biology courses 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): Geography in Education (1) Category: Pedagogy, teacher training and social care 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): Chemistry in Education (18) Category: Chemistry courses 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): Physical Education in Education (18) Category: Physical education and sport 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): German Language in Education (19) Category: Pedagogy, teacher training and social care 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): Information Technologies in Education (17) Category: Informatics courses 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): Geography in Education (17) Category: Pedagogy, teacher training and social care 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): Information Technologies in Education (16) Category: Informatics courses 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): Physical Education in Education (15) Category: Physical education and sport 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): Physical Education in Education (19) Category: Physical education and sport 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): Information Technologies in Education (15) Category: Informatics courses 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): Biology in Education (17) Category: Biology courses 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): Physics in Education (15) Category: Physics courses 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): Studies in Mathematics (17) Category: Mathematics courses 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): Physics in Education (17) Category: Physics courses 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): Physics in Education (16) Category: Physics courses 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Education Study plan (Version): Geography in Education (15) Category: Pedagogy, teacher training and social care 1 Recommended year of study:1, Recommended semester: Winter