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Lecturer(s)
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Polendová Daniela, MUDr.
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Jaklová Radka, MUDr.
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Course content
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Lectures: 1.History of genetics and its division. Cell cycle and mitosis. Meiosis. Gametogenesis in male and female. 2.Structure and function of DNA. Gene and genetic information transfer. 3.Mendel's laws. Basic terms:genotype, phenotype, dominance, recessivity, homozygote, heterozygote, types of heredity. 4.Caryotype, structure of chromosome. Investigative methods in cytogenetics. Origins and types of chromosomal abberations, numerical and structural chromosomal abberations. 5.Syndromes: Down, Edwards, Patau, cat cry, Klinefelter, XYY, Turner etc. 6.Investigative methods in molecular genetics, genetic engineering. 7.Genetic advisory and prenatal diagnostics of defects and congenital disorders. 8.Genetic disorders of human metabolism, options of treatment. 9.Impact of mutagenic factors of external environment and options of testing. 10.Ecogenetics. Pharmacogenetics. Immunogenetics. 11.Progress of carcinogenesis - types of mutations in selected types of malignities. Genetics and society.
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Learning activities and teaching methods
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Multimedia supported teaching, Lecture
- Contact hours
- 22 hours per semester
- Preparation for comprehensive test (10-40)
- 30 hours per semester
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| prerequisite |
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| Knowledge |
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| No particular prerequisites specified. |
| learning outcomes |
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| A graduate acquires knowledge about genetic information transfer and the impact of external environment on it, that he/she will apply after passing the course in practice. |
| teaching methods |
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| Lecture |
| Multimedia supported teaching |
| assessment methods |
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| Test |
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Recommended literature
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Fischlová, Hana. Základy genetiky. 1. vyd. V Plzni . Západočeská univerzita, 2011. ISBN 978-80-7043-973-9.
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Michalová, K. Úvod do lidské cytogenetiky. Brno, 1999.
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Snustad, D. Peter; Simmons, Michael J. Genetika. Vyd. 1. Brno : Masarykova univerzita, 2009. ISBN 978-80-210-4852-2.
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Šmarda, J. Genetika pro gymnázia.. Fortuna,, 2003. ISBN 80-7168-851-7.
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Thompson and Thompson. Klinická genetika.vydání. Triton, 2004. ISBN 80-72254-475-6.
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Vrba, M. Genetika pro zdravotní laboranty. BRNO, 1994.
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