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Lecturer(s)
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Svoboda Tomáš, MUDr. Ph.D.
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Course content
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Lectures 1. Definition of radiobiology, dosimetry 2. Basics of medical genetics, types of heredity. 3. Composition of living matter, cell and its components. 4. Cell cycle and cell division (compartments). 5. Biology of malignant tumors. 6. Radiosensitivity and radioresistance, radiocurability. 7. Physical basis of radiobiology, ionizing and non-ionizing radiation. 8. Linear energy transfer (LET). 9. - 10. Single hit and sub-lethal damage. 11. - 12. Biological dose equivalent (BED), conversion models - especially LQ 13. - 14. Oxygen effect. 15. Repetition.
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Learning activities and teaching methods
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- Contact hours
- 15 hours per semester
- Preparation for comprehensive test (10-40)
- 10 hours per semester
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| prerequisite |
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| Knowledge |
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| no prerequisites are prescribed |
| Skills |
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| no prerequisites are prescribed |
| Competences |
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| N/A |
| learning outcomes |
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| Knowledge |
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| defines the field of radiobiology |
| enumerates the types of heredity |
| explains cell cycle and cellular division |
| explains the terms radiosensitivity, radioresistance and radiocurability |
| defines ionizing and non-ionizing radiation |
| Skills |
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| are not defined |
| Competences |
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| N/A |
| N/A |
| teaching methods |
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| Knowledge |
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| Lecture |
| Competences |
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| Lecture |
| assessment methods |
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| Knowledge |
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| Test |
| Competences |
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| Test |
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Recommended literature
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Feltl, David; Cvek, Jakub. Klinická radiobiologie. Havlíčkův Brod : Tobiáš, 2008. ISBN 978-80-7311-103-8.
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Kuna, P., Navrátil, l. a kol. Klinická radiobiologie. Praha: Manus, 2005.
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Šlampa, P. a kol. Radiační onkologie v praxi. Brno: Masarykův onkologický ústav, 2007.
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