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Lecturer(s)
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Svoboda Tomáš, MUDr. Ph.D.
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Course content
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Lectures 1. Effect of radiation on a cell. 2. Tissue distribution by sensitivity to irradiation into classes (Rubin). 3. Tissue distribution according to irradiation response to individual types (F, H, F-H and tumor). 4. Growth theory of tumor population, intervention models. 5. Time factor - 4R. 6. Effect of radiation on organs - therapeutic width and ratio. 7. - 8. Fractionation, fractionation modes. 9. Damage by ionizing radiation (radiation syndrome and disease, professional damage), RBÚ. 10. Protection against ionizing radiation. 11. Repetition.
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Learning activities and teaching methods
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- Contact hours
- 11 hours per semester
- Preparation for comprehensive test (10-40)
- 10 hours per semester
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| prerequisite |
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| Knowledge |
|---|
| to define the field of radiobiology |
| to enumerate the types of heredity |
| to explain cell cycle and cellular division |
| to explain the terms radiosensitivity, radioresistance and radiocurability |
| to define ionizing and non-ionizing radiation |
| Skills |
|---|
| are not defined |
| Competences |
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| N/A |
| N/A |
| learning outcomes |
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| Knowledge |
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| characterizes the principles of radiation effects on cells, tissue and the whole organism |
| presents the processes caused by the passage of radiation |
| will clarify the importance of the required dose and fractionation regimen in radiotherapy of individual tumors, along with the need for radiation protection |
| Skills |
|---|
| are not defined |
| Competences |
|---|
| N/A |
| teaching methods |
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| Knowledge |
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| Lecture |
| Competences |
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| Lecture |
| assessment methods |
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| Knowledge |
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| Test |
| Competences |
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| Test |
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Recommended literature
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Feltl, D., Cvek, J. Klinická radiobiologie.. Havlíčkův brod:Tobiáš, 2008.
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Kuna, P., Navrátil, l. a kol. Klinická radiobiologie. Praha: Manus, 2005.
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Šlampa, P. Radiační onkologie v praxi. Brno: MOÚ, 2014. ISBN 978-80-86793-34-4.
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