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Lecturer(s)
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Ludvíková Marie, Doc. MUDr. Ph.D.
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Course content
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Lectures 1. Illness and its causes. Etiology and pathogenesis of diseases. Physical causes of the disease. Chemical causes of the disease. Genetic diseases. Pathological immune response. 2. Death of the organism and cell death (necrosis and apoptosis). Types of necrosis and its healing. Heart attack - definition, types of heart attacks. Gangrene. Atrophy. 3. Dystrophy from protein metabolism disorders. Inclusion. Amyloidosis. Diabetes mellitus. Pigmentation. Icterus (causes, types). 4. Inflammation, types of inflammation, microscopic and macroscopic findings. Inflammations specific. Overall infections (bacteraemia, sepsis, pyemia). 5. Progressive changes. Regeneration. Reparation. Hypertrophy, hyperplasia. Metaplasia, dysplasia and precancerosis. 6. Introduction to oncopathology. General properties of tumors. Tumor morphology. Properties of malignant tumors at the cellular level. Classification of tumors. Grading, staging. Diagnostic, prognostic and predictive tumor markers. Benign and malignant mesenchymal tumors. Haematological tumors. Benign and malignant epithelial tumors. 7. Causes and manifestations of circulatory insufficiency. Thrombosis. Hemorrhage, hemorrhagic diathesis. Embolism. Rival. Pathology and pathophysiology of cardiovascular system. Diseases of the heart and blood vessels. 8. Pathology and pathophysiology of respiratory system. Pathology and pathophysiology of the gastrointestinal system. Diseases liver, pancreas, gallbladder and biliary tract. 9. Pathology and pathophysiology of kidneys and urinary tract pathways. Prostate pathology. Pathology of the sexual system male and female. Diseases of the mammary gland. 10. Pathology of nervous and endocrine systems. Diseases of the musculoskeletal system.
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Learning activities and teaching methods
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- Preparation for an examination (30-60)
- 30 hours per semester
- Contact hours
- 30 hours per semester
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| prerequisite |
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| Knowledge |
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| describe the anatomy and explain the function of the organs of the human body |
| Skills |
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| are not required |
| Competences |
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| N/A |
| N/A |
| learning outcomes |
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| Knowledge |
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| enumerates the possible causes of diseases |
| explains the basic concepts of general pathology |
| describes the etiology, pathogenesis and consequence of impairment of function of individual organ systems |
| defines the causes and describes the manifestations of circulatory insufficiency |
| characterizes the possibilities of pathology in diagnosis, prognosis and prediction of diseases |
| Skills |
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| are not defined |
| Competences |
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| N/A |
| teaching methods |
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| Knowledge |
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| Lecture |
| Multimedia supported teaching |
| Skills |
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| Lecture |
| Competences |
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| Multimedia supported teaching |
| Lecture |
| assessment methods |
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| Knowledge |
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| Combined exam |
| Competences |
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| Combined exam |
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Recommended literature
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BÁRTOVÁ, J. Přehled patologie. Praha: Galén, 2015. ISBN 978-80-246-2745-8.
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MAČÁK, J., MAČÁKOVÁ, J., DVOŘÁČKOVÁ, J. Patologie.. Praha : Grada, 2012. ISBN 978-80-247-3530-6.
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POVÝŠIL, C., ŠTEINER, I. a kol. Speciální patologie.. Praha : Galén, 2007. ISBN 978-80-7262-494-2.
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Rokyta, Richard. Fyziologie a patologická fyziologie : pro klinickou praxi. 2015. ISBN 978-80-247-4867-2.
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Silbernagl, S., Lang, F. Atlas patofyziologie člověka. Praha: Grada, 2012. ISBN 978-80-247-3555-9.
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